River Plate vs Santa Fe — Prediction & Betting Tips

River Plate take on Santa Fe in the CONMEBOL Sudamericana on Thursday, 20 August 2026. Below is our data-driven preview and prediction for this fixture, based on head-to-head history and recent form.

In their last 4 meetings, River Plate have won 1, drawn 1 and lost 0 against Santa Fe. These fixtures have averaged 0.8 goals per game, with both teams scoring in 25% of them.

Defensively, River Plate kept 1 clean sheet and Santa Fe kept 1 across those meetings, giving a useful guide to how tight this matchup tends to be.